NAC vs Placebo on Opioid Use for Hysterectomy

ConditionHysterectomy
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University of South Carolina

About this trial

This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure. At various time points after the procedure patients will be asked to report their pain scores, and any pain medication taken.

Eligibility criteria

Qualifiers

Undergoing elective laparoscopic or robotic, full, or partial hysterectomy procedure

18 years of age and older

Less than 40kg in weight

Unable to provide written, informed consent

Disqualifiers

None

Trial design

Treatments tested in this trial

  • IV N-acetylcysteine
  • IV Placebo

Treatment groups

240 Participants
are divided into 2 treatment groups