About this trial
Anaemia is a common health problem in women. It is often due to iron deficiency. Anaemia is a particular problem during pregnancy and is bad for the mother and baby. It is best to treat anaemia in young women well before they get pregnant. Doctors treat anaemia with iron and vitamins. But some people get side effects when taking iron tablets and so they stop taking them. Heavy menstrual periods are a common cause of iron deficiency and even if women do take iron, because they lose so much iron in their periods, they still become iron deficient. Tranexamic acid (TXA) is a medicine used to treat heavy periods. The investigators of this study would like to find out if taking TXA with the usual iron and vitamin supplements is better at treating anaemia than taking iron and vitamin supplements alone. (Lay Summary)
Eligibility criteria
Qualifiers
Adult women (aged 18 years and older)
Having menstrual periods every 21 to 38 days that last 2 to 9 days
Having anaemia (Hb < 120 g/L) according to point-of-care finger prick screening test
Willing to provide informed consent and able to attend study visits during the trial period
Disqualifiers
Planning to get pregnant during trial period
Already taking TXA
Known to have contraindications to TXA treatment (including allergy to TXA or its excipients, renal impairment, active thromboembolic disease, history of venous or arterial thrombosis, history of convulsion.)
Trial design
Treatments tested in this trial
- Tranexamic Acid 500 MG
- Matched placebo
Treatment groups
Locations
Sponsors and collaborators
London School of Hygiene and Tropical Medicine
Lead sponsor
The Jon Moulton Charity Trust
Collaborator