VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

ConditionsAsthma Respiratory Tract Infections Gastrointestinal Infection Croup Eczema Allergy Wheezing Fractures, Bone Development, Child Cognition Disorders in Children Psychiatric Diagnosis

Trial statusRecruiting

Trial phasePhase 3

Trial typeInterventional

Biological sexFemale

Age18-45

SponsorProfessor Klaus Bønnelykke

About this trial

The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that supplementation in higher doses than recommended could reduce the risk of disease development.

Eligibility criteria

Qualifiers

Pregnant Danish women before week 26 with blood levels of EPA+DHA above 4.7% of total fatty acids

No current vitamin D intake above the recommended 400 IU/day

No endocrine-, heart-, kidney- or auto-immune disorders

No disorders requiring treatment with blood thinning medication

Disqualifiers

None

Trial design

Treatments tested in this trial

Cholecalciferol D3
Olive oil

Treatment groups

2,000 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Professor Klaus Bønnelykke

Lead sponsor

Copenhagen Studies on Asthma in Childhood

Sponsor institution

Source ClinicalTrials.gov