APPI-Cost Trial for Perforated Appendicitis
ConditionPerforated Appendicitis
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe University of Texas Health Science Center, Houston
About this trial
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.
Eligibility criteria
Qualifiers
Plan to undergo appendectomy for acute appendicitis
Disqualifiers
Preoperative hemodynamic instability requiring ongoing infusion of vasopressors
Allergy to iodine
Uncontrolled hyper- or hypothyroidism
Renal dysfunction
Trial design
Treatments tested in this trial
- PVI
- Usual Care
Treatment groups
346 Participants
are divided into 2 treatment groupsSponsors and collaborators
The University of Texas Health Science Center, Houston
Lead sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborator
Source ClinicalTrials.gov