Appropriate Dosage of Vasopressor in Neonates and Infants
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
AgeUp to 2
SponsorSeoul National University Hospital
About this trial
In this study, the investigators will evaluate cerebral blood flow before and after drug infusion using ultrasound to suggest blood pressure criteria and dosage of ephedrine, a vasopressor, to maintain adequate cerebral blood flow in neonates and infants undergoing surgery and anesthesia.
Eligibility criteria
Qualifiers
Newborns and infants under 2 years of age undergoing surgery under general anesthesia at Seoul National University Hospital
Disqualifiers
Premature infants with a gestational age of less than 37 weeks
Children with a history of brain disease (hydrocephalus, brain tumor, etc.)
Patients with a history of hypoxic/ischemic brain injury
Children with fused fontanels
Trial design
Treatments tested in this trial
- EPHEDrine Hydrochloride 5 mg/ml
Treatment groups
132 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Locations
Sponsors and collaborators
Source ClinicalTrials.gov