About this trial
Over 80% of patients who undergo surgery suffer from acute postoperative pain, with 75% of them rating the pain severity as moderate, severe, or extreme. Studies have shown that less than 50% of patients who undergo surgery report adequate relief from postoperative pain.
Additionally, if pain is not promptly managed after surgery, it can hinder a patient's ability to walk, potentially causing adverse effects such as thromboembolism, myocardial ischemia, and arrhythmia.
The opioid analgesics are most commonly used as parenteral agents to manage post operative pain but the problem of respiratory depression remains to be considered.
This study is designed to compare the analgesic effect between dexmedetomidine versus magnesium sulfate as adjuvant to bupivacaine using ultrasound guided Transversus Abdominis Plane block in patients undergoing abdominal hysterectomy
Eligibility criteria
Qualifiers
ASA classification I-ll,
Aged >18 years,
weight 50-85 kg,
Patients who will undergo total abdominal hysterectomy
Disqualifiers
• ASA classification I-ll,
Aged >18 years,
weight 50-85 kg,
Patients who will undergo total abdominal hysterectomy
Trial design
Treatments tested in this trial
- bupivacaine 0.5%
- Dexmedetomidine
- MgSO4