Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate as Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : A Randomized Double-blinded Study

ConditionHysterectomy
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Over 80% of patients who undergo surgery suffer from acute postoperative pain, with 75% of them rating the pain severity as moderate, severe, or extreme. Studies have shown that less than 50% of patients who undergo surgery report adequate relief from postoperative pain.

Additionally, if pain is not promptly managed after surgery, it can hinder a patient's ability to walk, potentially causing adverse effects such as thromboembolism, myocardial ischemia, and arrhythmia.

The opioid analgesics are most commonly used as parenteral agents to manage post operative pain but the problem of respiratory depression remains to be considered.

This study is designed to compare the analgesic effect between dexmedetomidine versus magnesium sulfate as adjuvant to bupivacaine using ultrasound guided Transversus Abdominis Plane block in patients undergoing abdominal hysterectomy

Eligibility criteria

Qualifiers

ASA classification I-ll,

Aged >18 years,

weight 50-85 kg,

Patients who will undergo total abdominal hysterectomy

Disqualifiers

• ASA classification I-ll,

Aged >18 years,

weight 50-85 kg,

Patients who will undergo total abdominal hysterectomy

Trial design

Treatments tested in this trial

  • bupivacaine 0.5%
  • Dexmedetomidine
  • MgSO4

Treatment groups

64 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators