Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
ConditionAcne Vulgaris
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age9+
SponsorIntegrative Skin Science and Research
About this trial
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline. The bacteria in the gut and on the skin will be studied to see how each treatment may affect them and whether they change the profile of the bacteria that is present.
Eligibility criteria
Qualifiers
At least 10 inflammatory lesions (papules, pustules, and nodules) up to 100 noninflammatory lesions (open and closed comedones)
No more than 2 nodules on the face
Disqualifiers
Dermatological condition of face or facial hair that could interfere with clinical evaluations
Topical acne medications such as retinoids, antibiotics, hormonal modulators
Topical benzoyl peroxide
Topical anti-inflammatories and corticosteroids
Trial design
Treatments tested in this trial
- Sarecycline
- Doxycycline
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Integrative Skin Science and Research
Lead sponsor
Almirall, S.A.
Collaborator
Source ClinicalTrials.gov