About this trial
The goal of this clinical trial is to compare norepinephrine and ephedrine in maintaining blood pressure during spinal anaesthesia for elective cesarean delivery. The main questions it aims to answer are:
* Do phenylephrine and norepinephrine administered as manually controlled continuous infusion during elective cesarean delivery have different effects on neonatal outcome ? * Do phenylephrine and norepinephrine administered as manually controlled continuous infusion during elective cesarean delivery have different effects on maternal hemodynamics? Participants will receive either phenylephrine or norepinephrine infusion, at the time of performing spinal anesthesia, the infusion rate will be adjusted manually depending on maternal arterial pressure.
Eligibility criteria
Qualifiers
Full-term, singleton, pregnant women, nonlaboring.
Scheduled for elective cesarean delivery under spinal anesthesia,
American Society of Anesthesiologists physical status : 1 or 2
Baseline systolic BP between 90 and 140 mm Hg.
Disqualifiers
Known fetal abnormality.
Preexisting or pregnancy-induced hypertension, cardiovascular, cerebrovascular or kidney disease.
Contraindication to spinal anesthesia.
Peripartum hemorrhage.
Trial design
Treatments tested in this trial
- Continuous infusion of Norepinephrine
- Continuous infusion of Phenylephrine