Clinical trials

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Condition / disease
Location
Status: Recruiting

Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE)

The goal of this clinical trial is to compare norepinephrine and ephedrine in maintaining blood pressure during spinal anaesthesia for elective cesarean delivery. The main questions it aims to answer are: * Do phenylephrine and norepinephrine administered as manually controlled continuous infusion during elective cesarean delivery have different effects on neonatal outcome ? * Do phenylephrine and norepinephrine administered as manually controlled continuous infusion during elective cesarean delivery have different effects on maternal hemodynamics? Participants will receive either phenylephrine or norepinephrine infusion, at the time of performing spinal anesthesia, the infusion rate will be adjusted manually depending on maternal arterial pressure.

Participants needed: 140
Trial details
Phase: Phase 4Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Hassan II UniversityUpdated: Sep 9, 2025Locations: 2
Eligibility criteria

Full-term, singleton, pregnant women, nonlaboring. [+3]

Known fetal abnormality. [+4]