Dose Dependent Steroid Injections

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Miami

About this trial

This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and function in lumbar radiculopathy at varying doses, and to evaluate difference in efficacy between triamcinolone and dexamethasone interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, with the overarching hypotheses that there is no difference in reported pain reduction, quality of life, or function among patients receiving low, moderate, or high doses, and no difference in reported pain reduction between triamcinolone and dexamethasone.

Eligibility criteria

Qualifiers

Adults able to consent

Lumbar radiculopathy with MRI-confirmed pathology

No history of back surgery

Use of interlaminar approach lumbar spine injections

Disqualifiers

Adults unable to consent

Individuals who are not yet adults (infants, children, teenagers)

Pregnant women

History of back surgery

Trial design

Treatments tested in this trial

  • Triamcinolone 10 Mg/mL Injectable Suspension
  • Triamcinolone 40 Mg/mL Injectable Suspension
  • Triamcinolone 80 Mg/mL Injectable Suspension
  • Dexamethasone 2 MG
  • Dexamethasone 4mg
  • Dexamethasone 8 MG

Treatment groups

150 Participants
are divided into 6 treatment groups

6

Treatment groups

See each treatment group below.

Sponsors and collaborators