"Effect of Ibuprofen on Acute Inflammatory Response After One-Stage Periodontal Therapy"
ConditionPeriodontitis
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Baghdad
About this trial
The goal of this ( Clinical Trial ) is to evaluate the efficacy of Ibuprofen in reducing acute inflammatory response (hs-CRP, ProCT, IL-6) after one hour and one week following one stage non surgical periodontal therapy.
The main question it aims to answer is:
"Does Ibuprofen effectively reduce the acute inflammatory response ( hs-CRP, ProCT, IL-6) following one-stage non-surgical periodontal therapy?"
Eligibility criteria
Qualifiers
systemically healthy patients.
having a minimum of 20 teeth.
Generalized unstable periodontitis.
Pocket depth [≥ 4 mm].
Disqualifiers
Allergy or hypersensitivity to Ibuprofen or other NSAIDs.
current systemic anti-inflammatory or antibiotic therapy (<3 months).
peptic ulcer disease.
recent periodontal therapy (<3 months).
Trial design
Treatments tested in this trial
- Non surgical root surface debridement in one stage without receiving Ibuprofen
- Non surgical root surface debridement in one stage with receiving Ibuprofen
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov