Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAydin Adnan Menderes University

About this trial

The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are:

What medical conditions do participants have while taking ozonated water and hypochlorous acid solution?

Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa.

Participants:

Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.

Eligibility criteria

Qualifiers

Be between the ages of 18-65,

Have been on mechanical ventilation for at least 24 hours,

Have no intolerance or allergy to the solutions,

Agree to participate in the study

Disqualifiers

Having a contraindication for oral care

Not agreeing to participate in the study

Trial design

Treatments tested in this trial

  • Control 1

Treatment groups

63 Participants
are divided into 3 treatment groups