Oral Mucosal Disorder

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Review clinical trials related to Oral Mucosal Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Prevalence of Oral Mucosal Lesions Among a Sample of Adult Egyptian Subjects

Oral mucosal lesion represents a wide array of conditions. They may be the result of a local or systemic infection or trauma or the manifestations of a medical condition or neoplastic growth weather primary or metastatic or may be mistaken for a variation of a normal structure. This study aims to estimate the prevalence of OMLs and describe the risk factors for the development of OMLs in a sample of the Egyptian population Research Question :What is the prevalence of oral mucosal lesions and their associated risk factors in a sample of adult Egyptians?

Participants needed: 14,645
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Cairo UniversityUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Adults, 18 years old and above, Egyptian individuals

Individuals refusing to participate in the study. Individuals unable to give acc...

Status: Not yet recruiting

Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa

The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are: What medical conditions do participants have while taking ozonated water and hypochlorous acid solution? Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa. Participants: Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.

Participants needed: 63
Trial details
Phase: Phase 4Age: 18-65Biological sex: AllType: InterventionalSponsor: Aydin Adnan Menderes UniversityUpdated: Apr 24, 2025Locations: 1
Eligibility criteria

Be between the ages of 18-65, [+3]

Having a contraindication for oral care [+1]

Status: Recruiting

Perioral Tissue Evaluation With Advanced Videodermoscopy (FAV)

The primary aim of this study is to characterize and systematically document the key dermato-mucosal structures of the perioral region in physiological conditions. Relative to the anterior chin area (ACA), the authors have tried to identify and describe pores, fine lines or wrinkles, texture patterns, superficial desquamation, hair follicles, sebaceous glands, fine ridges, grooves, sebaceous ducts, and skin irregularities. The observed features of the vermilion border (VB) and vermilion zone (VZ) include variations in color, texture, and surface characteristics, alongside the presence of fine lines and grooves. Vascular patterns and capillary visibility were observed, with pigmentation patterns providing additional insights into structural uniformity and non-uniform areas. Shiny surfaces, pore visibility, and regional differences in sebaceous activity and texture were also highlighted, reflecting the complex variability across the vermilion zone. Additionally, novel dermatoscopic and FAV findings not previously described in the literature were introduced into the analysis based on the personal observations of the investigators. This allowed for a comprehensive evaluation of the skin characteristics, providing a detailed analysis for each anatomical zone studied.

Participants needed: 80
Trial details
Age: 20-35Biological sex: AllType: ObservationalSponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCSUpdated: Dec 13, 2024Locations: 1
Eligibility criteria

Age: Participants must be between 20 and 35 years old [+5]

Dermatological Disorders: History of skin diseases (e.g., acne, psoriasis, eczem... [+7]