Effects of Flurbiprofen Spray and Ice Cream for Pain and Voice Outcomes After Thyroidectomy
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-85
SponsorIzmir Katip Celebi University
About this trial
Researchers will compare oral flurbiprofen (%0.25) spray and ice cream to a placebo (a look-alike substance that contains no drug) to see if oral flurbiprofen (%0.25) spray and ice cream works to effect post-thyroidectomy throat pain and voice quality.
Participants will:
* Receive 1 puff of oral flurbiprofen (0.25%) spray or 105 ml of ice cream or 1 puff of oral spray prepared with drinking water (placebo) at 5 hours postoperatively according to randomization result * Undergo voice analysis using Praat voice analysis (University of Amsterdam) at 6 hours postoperatively * Undergo a visual analog scale for analgesia status at 6 hours postoperatively
Eligibility criteria
Qualifiers
No history of neck surgery
Age between 18-85 years
Undergoing thyroidectomy
Agreeing to participate in the study
Disqualifiers
History of neck surgery
History of radiotherapy to the head and neck region
Pre-operative or post-operative vocal cord paralysis
Pre-operative phonetic disorder
Trial design
Treatments tested in this trial
- Flurbiprofen
- Food Effect cohort
- Placebo Control
Treatment groups
100 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov