This study is a randomized clinical trial that compares the effectiveness of Plasma Rich in Growth Factors (PRGF) with conventional treatment for healing foot ulcers in diabetic patients who also have peripheral arterial disease. The goal is to assess how well PRGF promotes healing over a six-month period.
Patients aged at least 18 years
Diagnosis of type 1 or 2 diabetes
Presence of one or more ulcers below the malleoli
Ulcer size ranging from 1 to 25 cm2
Ulcers grade 3 or higher
Positive markers for HCV, AfHBs, HIV-I/II or TP
Diabetes mellitus with poor metabolic control (evidence of glycosylated hemoglobin >9%)
Active systemic infection
Biotechnology Institute IMASD
Lead sponsor
Hospital de Basurto
Collaborator