Impact of Preoperative Quadratus Lumborum Block on Postoperative Opioid Consumption After Laparoscopic Hysterectomy

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age18+
SponsorWalter Reed National Military Medical Center

About this trial

The goal of this clinical trial is to learn if preoperative nerve block (quadratus lumborum \[QL\] block) works to improve pain control during and after laparoscopic hysterectomy. The main questions it aims to answer are:

Does QL block decrease the amount of narcotic medication needed during surgery? Does QL block decrease the amount of narcotic medication needed after surgery?

Researchers will compare QL block to local injection of a numbing medication at each incision site (the current standard practice) to see if QL block works to decrease surgical pain.

Participants will be randomly assigned to receive one of the two following interventions:

1. QL block before surgery with a long-acting numbing medicine (liposomal bupivacaine) and then injection of placebo (saline) at each incision site in the operating room. 2. QL block before surgery with placebo (saline) and then injection of local numbing medicine (bupivacaine) at each incision site in the operating room.

Participants will also:

* Visit the clinic/hospital for a pre-operative appointment, the surgical procedure, and a 4-6 week post-operative appointment (all standard visits even if not participating in research) * Complete a questionnaire electronically, or by phone, that takes \<10 minutes at the pre-operative appointment and on postoperative days 1, 3, 5, 14, and 4-6 weeks.

Eligibility criteria

Qualifiers

18 years or older

scheduled to undergo laparoscopic hysterectomy

able to speak and understand English

DEERs eligible (eligible for healthcare within military heath system)

Disqualifiers

pre-operative opioid use

pre-operative pain management clinic patient

planned concomitant prolapse or incontinence procedure

planned concomitant non-gynecologic abdominal procedure (i.e. hernia repair)

Trial design

Treatments tested in this trial

  • Quadratus Lumborum Block (QLB)
  • Quadratus lumborum block
  • Local Anesthetic Solution
  • Local Anesthetic Solution

Treatment groups

76 Participants
are divided into 2 treatment groups