Methadone in the Management of Post-Operative Pain in Total Knee Replacement
ConditionTotal Knee Arthroplasty
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age21-75
SponsorAdventHealth
About this trial
The goal of this study is to determine whether one dose of IV methadone given right before surgery will help patients' pain management after a total knee replacement and reduce the amount of pain medications taken in the weeks after surgery.
Eligibility criteria
Qualifiers
Provision of signed and dated informed consent from
Stated willingness to comply with all study procedures and availability to attend all required visits for the duration of the study.
Age 21- 75
Unilateral total knee arthroplasty at Colorado Joint Replacement
Disqualifiers
Narcotic use in the past 6 weeks
Current or previous history of drug and alcohol abuse
Tobacco use in the previous 90 days
Treatment with another investigational drug
Trial design
Treatments tested in this trial
- Methadone
Treatment groups
192 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov