To find out whether oral antibiotics given after transsphenoidal endoscopic surgery for pituitary adenoma improves sinus and nasal symptoms, reduces the incidence of infection (sinusitis), and helps mucosal healing in the nasal passages.
Adult patient undergoing endoscopic surgery for resection of pituitary tumors for nonfunctioning adenoma, acromegaly, or prolactinoma
Adults >18 and <85 years of age
English speaking and able to understand the ASK Nasal-12 and SNOT-22 scales
Free of any physical, mental, or medical condition which, in the opinion of the investigator, makes study participation inadvisable
Anaphylaxis/intolerance to the study drugs
Cirrhosis, hepatitis
Any solid organ transplant or bone marrow transplant. And any patient felt to be immunocompromised by the investigators
Renal failure on dialysis
St. Joseph's Hospital and Medical Center, Phoenix
Lead sponsor
Thomas Jefferson University
Collaborator
The Cleveland Clinic
Collaborator