The present study is aimed to compare the safety and efficacy of Ticagrelor with low-dose Aspirin versus standard dual anti-platelet therapy (DAPT) in patients with acute coronary syndrome (ACS) at high risk for ischemic events after percutaneous coronary intervention (PCI) and stent implantation.
ACS patients at high risk for ischemic events after successful PCI with implantation of at least one drug eluting stent
Able and willing to provide informed consent and participate in 12 months follow-up period
Able to receive DAPT treatment
Enrollment into the study will require meeting at least one angiographic or clinical inclusion and none of the
Family history of premature coronary heart disease (Coronary heart disease in first-degree male relative <55 years old or in first-degree female relative <65 years old)
Repeated myocardial infarction
Positive serum cardiac troponin I/T
Combined with at least one organ/system with atherosclerotic disease (e.g. intracranial or peripheral arteries)