Physiologic Change of Posterior Ocular Segment During Pregnancy
ConditionRetinal Vascular
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorKhon Kaen University
About this trial
Women's physiology changes markedly during normal pregnancy. The most distinct alterations occur in the hormonal and cardiovascular systems. There is a dramatic increase in both estrogen and progesterone. Blood volume starts to increase in the first gestational period and reaches a peak in the third trimester.
The physiologic ocular changes during pregnancy are mainly the result of hormonal and blood volume increase, and then are usually marked in the third trimester.
Eligibility criteria
Qualifiers
Healthy pregnant women
Age > 18 years
Gestational age < 12 weeks
Written informed consent
Disqualifiers
High risk pregnancy such as multifetal pregnancy and preeclampsia
History of vitreoretinal diseases such as retinal vasculitis
History of intraocular laser treatments or intraocular surgeries
History of systemic diseases such as diabetes mellitus and thyroid disease
Trial design
Treatments tested in this trial
- Optical coherence tomography and optical coherence tomography angiography (Optovue®)
Treatment groups
69 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov