Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorXiaoJing Zou,MD
About this trial
This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.
Eligibility criteria
Qualifiers
Diagnosed with ARDS according to the 2023 global new definition of ARDS.
Age ≥ 18 years.
Disqualifiers
Severe chronic obstructive pulmonary disease, severe asthma, pulmonary bullae, pneumothorax, subcutaneous emphysema, mediastinal emphysema, etc. · Contraindications for EIT, such as chest wound dressing, pacemaker implantation, defibrillator use, etc.
Pulmonary interstitial disease.
Uncorrected shock of various types.
Intracranial hypertension.
Trial design
Treatments tested in this trial
- EIT-guided Phigh settings during APRV
Treatment groups
26 Participants
are divided into 2 treatment groupsSponsors and collaborators
XiaoJing Zou,MD
Lead sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sponsor institution
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborator
Source ClinicalTrials.gov