Pralatrexate Combined With Chidamide Bridging Allogeneic HSCT for Refractory/Relapsed Peripheral T-cell Lymphoma

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorPeking University People's Hospital

About this trial

This is a multicenter, prospective study of Pralatrexate combined with Chidamide bridging Allogeneic Hematopoietic Stem Cell Transplantation for Refractory/Relapsed Peripheral T-cell Lymphoma

Eligibility criteria

Qualifiers

Patients fully understand the study, voluntarily participate in and sign on the informed consent;

Diagnosed by histopathology Peripheral T-cell lymphoma;

ECOG PS score 0 or 1;

Relapsed or Refractory Peripheral T Cell Lymphoma;

Disqualifiers

NK/T-cell lymphoma;

Achieving CR or PR after induction chemotherapies without relapse;

Dysfunction of vital organs;

Serious history of autoimmune diseases and immunodeficiency, including: positive for human immunodeficiency virus (HIV) antibodies; Or other acquired or congenital immunodeficiency diseases; Or have a history of organ transplantation;

Trial design

Treatments tested in this trial

  • Pralatrexate combined with Chidamide bridging Allogeneic Hematopoietic Stem Cell Transplantation

Treatment groups

25 Participants
are divided into 1 treatment group

Sponsors and collaborators

Peking University People's Hospital

Lead sponsor

Ruijin Hospital

Collaborator

Wuhan TongJi Hospital

Collaborator

West China Hospital

Collaborator