Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorGerman Institute of Human Nutrition
About this trial
The objective of this study is to investigate the impact of hypocaloric time-restricted eating (TRE) at different day times (early versus late TRE) on glucose metabolism and other cardiometabolic parameters in individuals with overweight and with normal, or impaired glucose metabolism (prediabetes and type 2 diabetes). In addition, the study aims to elucidate the molecular mechanisms underlying these effects.
Eligibility criteria
Qualifiers
Overweight or obesity (BMI 25-40 kg/m²)
Healthy glucose metabolism (fasting glucose <100 mg/dl and glucose after 2 hours OGTT <140 mg/dl)
OR impaired glucose metabolism (fasting glucose 100-125 mg/dl and/or glucose after 2 hours OGTT 140-199 mg/dl and/or HbA1c 5.7-6.4%)
OR type 2 diabetes (according to existing medical diagnosis or fasting glucose >126 mg/dl and/or glucose after 2 hours OGTT >200 mg/dl and/or HbA1c ≥6.5%)
Disqualifiers
Weight changes > 5% within past 3 months
Shift work
Traveling across more than one time zone within one month prior to the study
Pregnancy and breastfeeding
Trial design
Treatments tested in this trial
- Early Time-Restricted Eating
- Late Time-Restricted Eating
Treatment groups
30 Participants
are divided into 2 treatment groupsLocations
1Map coordinates are unavailable for these locations. Locations are shown below instead.
German Institute of Human Nutrition Potsdam-RehbrueckeRecruiting14558, Nuthetal
Germany
GermanySponsors and collaborators
German Institute of Human Nutrition
Lead sponsor
Technische Universität Dresden
Collaborator
University of Surrey, UK
Collaborator
University of Geneva, Switzerland
Collaborator
Technische Universität München, Germany
Collaborator
German Center for Diabetes Research
Collaborator
University of Rovira i Virgili, Spain
Collaborator
Source ClinicalTrials.gov