Prediction of Local Anaesthetic Dosing During Labour Epidural Analgesia

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

About this trial

Epidural analgesia is the gold standard for controlling labour pain. However, labour pain happens during neuraxial analgesia, due to anaesthetic, obstetric, maternal factors.

The investigators hypothesized that relevant variables, able to predict the local anaesthetic (LA) requirement during labour, can be identified at admission and each parturient may therefore be accordingly classified in "low-requirement" and "high-requirement". In this way, a predictive score may be developed, and the analgesic regimen may be matched to the individual patient, thus ensuring a timely and appropriate treatment of patients likely to require higher doses of LA, while minimizing potentially side effects of excessive treatment in the low-dose group.

Eligibility criteria

Qualifiers

Parturients receiving neuraxial analgesia for labour, as clinical practice

Disqualifiers

Planned caesarean delivery

Trial design

Treatments tested in this trial

  • Machine-learning prediction model

Treatment groups

12,500 Participants
are divided into 1 treatment group