Prevalence of Treponema Parvum in Subgingival Microbiome of Patients With Periodontitis

ConditionPeriodontitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30+
SponsorUniversity of Baghdad

About this trial

The current study primarily aims to evaluate the presence of T. parvum in periodontal health and disease, and its correlation with clinical parameters. Subgingival plaque samples will be collected using sterile paper points then the samples will be analyzed using quantitative polymerase chain reaction (qPCR) to detect T. parvum and estimate its relative amount in the biofilm. The results may help clarify the association between T. parvum and periodontitis.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Study population involves those who are attending the clinics of Periodontics in the College of Dentistry / University of Baghdad, in Baghdad / Iraq, and seeking for periodontal treatment. Eligible patients according to the pre-defined inclusion and exclusion criteria who will be invited to participate in this study.

Trial design

Design model

Case-control

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

112 Participants
are grouped into 2 trial groups
Group A: Periodontitis
Group B: Healthy periodontium

Trial outcomes

Primary outcomes

1

Relative abundance of T. parvum in subgingival biofilm

Detection and relative abundance of T. parvum in subgingival biofilm measured by qPCR from subgingival plaque collected using sterile paper points

Time frame
At enrollment

Secondary outcomes

Other outcomes

Sponsors and contacts

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