About this trial
The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients.
The main questions that the study should answer:
What are the main risk factors for the development of intestinal dysfunction? What specific and non-specific biomarkers can predict the development of intestinal dysfunction? The study participants will be monitored from the moment of hospitalization until the end of their stay in a medical facility
Eligibility criteria
Qualifiers
Surgery on the heart and main vessels with a high risk of developing gastrointestinal dysfunction (according to literature data and our own retrospective study);
Patient's consent to participate in the study
Disqualifiers
Patient's refusal to participate in the study;
HIV infection in the patient;
Immunosuppressive therapy;
Oncological disease;
Trial design
Treatments tested in this trial
- additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure
Treatment groups
Sponsors and collaborators
Petrovsky National Research Centre of Surgery
Lead sponsor
Negovsky Reanimatology Research Institute
Collaborator
Lomonosov Moscow State University Medical Research and Educational Center
Collaborator