Prognosis and Diagnosis of Acute Gastrointestinal Dysfunction in Cardiac Surgery Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-95
SponsorPetrovsky National Research Centre of Surgery

About this trial

The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients.

The main questions that the study should answer:

What are the main risk factors for the development of intestinal dysfunction? What specific and non-specific biomarkers can predict the development of intestinal dysfunction? The study participants will be monitored from the moment of hospitalization until the end of their stay in a medical facility

Eligibility criteria

Qualifiers

Surgery on the heart and main vessels with a high risk of developing gastrointestinal dysfunction (according to literature data and our own retrospective study);

Patient's consent to participate in the study

Disqualifiers

Patient's refusal to participate in the study;

HIV infection in the patient;

Immunosuppressive therapy;

Oncological disease;

Trial design

Treatments tested in this trial

  • additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure

Treatment groups

100 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Petrovsky National Research Centre of Surgery

Lead sponsor

Negovsky Reanimatology Research Institute

Collaborator

Lomonosov Moscow State University Medical Research and Educational Center

Collaborator