Health TrialsbyHealthPanel

Prone Position Assessed by 3D EIT

ConditionsARDS (Acute Respiratory Distress Syndrome)Respiratory Failure
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorPeking Union Medical College Hospital

About this trial

To investigate global and regional changes in lung ventilation and perfusion induced by prone position in ARDS patients assessed by 3D-EIT. And to investigate the difference between 2D-EIT and 3D-EIT in prone position monitoring.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients on mechanical ventilation.

Diagnosis of ARDS was based on the Berlin definition

Patients in need of prone position because of clinical condition

Disqualifiers

Under 18 years of age.

Pregnant women;

Ribcage malformation

Any contraindication to the use of EIT (e.g. automatic implantable cardioverter defibrillator, and implantable pumps).

Trial population

Patients with ARDS on mechanical ventilation

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Prone position

    Behavioral

    Patients were ventilated based on the ARDS-Net recommendations . Patients were kept in a supine position. The process of lung ventilation and perfusion assessment was as follows: 1. PEEP was determined by the attending doctor and was kept the same during the supine and prone period. 2. 3D-EIT was used to monitor the ventilation and perfusion of ARDS patients at three timepoints: T1: supine position, T2: prone position at 30min, T3: prone position over 10 hours.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Regional ventilation monitored by EIT

Using EIT to monitor the regional ventilation during supine and prone position, to monitor the ventilation distribution change.

Time frame
5-10minutes
2

Regional perfusion monitored by EIT

Using EIT to monitor the regional perfusion during supine and prone position, to monitor the ventilation distribution change.

Time frame
5-10minutes
3

V/Q monitored by EIT

Ventilation and perfusion monitored by EIT in supine and prone position. To evaluate the V/Q match, deadspace and shunt lung region.

Time frame
5-10minutes

Secondary outcomes

1

Respiratory system compliance

Monitor the respiratory system compliance during supine and prone position

Time frame
1 day
2

SpO2

Monitor the SpO2 during supine and prone position

Time frame
1 day

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Peking Union Medical College Hospital

Lead sponsor

Source ClinicalTrials.gov
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