About this trial
The impact of cerebrovascular procedures on patients experiencing anxiety and depression is not well studied despite the high prevalence of these mental health disorders. Unruptured Intracranial aneurysms (UIAs) have a prevalence of approximately 3% and an annual risk of 1-2% in the general population. Despite the high risk of fatality following aneurysm rupture with a rate of 40-50%, the overall aneurysm growth and rupture risks are rare (less than 3% per aneurysm per year) and many patients can be observed with serial follow-up imaging over years. Nevertheless, due to the gravity of the bad consequences of aneurysm rupture, simply informing many patients of UIA diagnosis has been found to result in worse outcomes of health-related quality of life. This study aims to investigate the impact of awareness of untreated UIA on the patients' mental health utilizing the Hospital Anxiety and Depression Scale (HADS) tool.
Eligibility criteria
Qualifiers
Unruptured intracranial aneurysms (UIA)
mRS scores between 0-1
Observation Group: All patients with UIAs that are eligible for conservative management
Specific locations that are not good candidates for interventional treatment, such as cavernous internal carotid artery and very distally located aneurysms
Disqualifiers
Prior history of Subarachnoid Hemorrhage (SAH)
Prior history of intracranial aneurysm
Severe comorbidities that impact the mental health of the patients, such severe psychiatric disease, and chronic end stage diseases
Traumatic, mycotic, dissecting, or fusiform aneurysms
Trial design
Treatments tested in this trial
- Clipping
- Endovascular embolization
- Surveillance imaging
Treatment groups
Sponsors and collaborators
Montefiore Medical Center
Lead sponsor
The Bee Foundation
Collaborator