Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorLawson Research Institute of St. Joseph's

About this trial

Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID. This feasibility trial will evaluate a new rehabilitation program called COVIDEx for treating fatigue after COVID-19, and compare its effectiveness to the standard treatment currently used. The experimental treatment group will receive an 8-week multi-modal rehabilitation program with two 50-minute sessions per week. 60 participants will be recruited, randomly assigned to the COVIDEx program or standard of care (SoC) and followed for 24 weeks.

Eligibility criteria

Qualifiers

Adults of at least 18 years of age

Able to provide informed consent

Can speak and understand English

Documented history of SARS-CoV-2 infection (positive PCR/antigen test during acute illness or clinical diagnosis by physician during or after the acute illness)

Disqualifiers

Active SARS-CoV-2 infection

Pre-existing physical, cognitive, and/or mental health conditions that make exercise contraindicated, consent unattainable, or that cause symptoms similar to those seen in post COVID-19 (e.g., major neurocognitive disorder, schizophrenia, chronic fatigue syndrome) that could affect data

Inability to follow study procedures

Pregnant and/or breastfeeding

Trial design

Treatments tested in this trial

  • COVIDEx

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Lawson Research Institute of St. Joseph's

Lead sponsor

Western University, Canada

Collaborator

Canadian Institutes of Health Research (CIHR)

Collaborator