Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study

ConditionsCholangiocarcinoma, Extrahepatic Cholangiocarcinoma of the Extrahepatic Bile Duct Cholangiocarcinoma, Perihilar Diagnosis Raman Spectroscopy Klatskin Tumor Endoscopy Biliary Stricture Malignant Biliary Stricture

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorUniversity Hospital Olomouc

About this trial

Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.

Eligibility criteria

Qualifiers

person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP

Disqualifiers

disagreement with the study

Trial design

Treatments tested in this trial

Endoscopic retrograde cholangiopancreatography (ERCP)

Treatment groups

20 Participants

are divided into 1 treatment group

Sponsors and collaborators

University Hospital Olomouc

Lead sponsor

Palacky University

Collaborator

Source ClinicalTrials.gov