About this trial
The goal of this pragmatic randomized clinical trial is to determine whether an Epic-based clinician notification increases initiation of guideline-directed cardio-kidney-metabolic (CKM) therapies in adults with type 2 diabetes and confirmed albuminuria.
The main question it aims to answer is:
• Does an Epic clinician notification improve initiation of guideline-directed CKM therapies compared with usual care?
Researchers will compare an Epic in-basket clinician notification strategy with usual care.
In the intervention arm, the treating clinician will receive an Epic notification identifying confirmed albuminuria and potential eligibility for guideline-directed CKM therapies using existing electronic health record (EHR) data. Participants in the usual care arm will receive standard clinical care without notification.
Eligibility criteria
Qualifiers
Adults aged ≥18 years
Diagnosis of type 2 diabetes mellitus
Receiving outpatient care within Baylor Scott & White Health
At least 1 outpatient encounter within the preceding 12 months
Disqualifiers
Type 1 diabetes mellitus
Contraindication or documented intolerance to all eligible guideline-directed CKM therapies
Advanced kidney dysfunction below recommended initiation thresholds for SGLT2i or finerenone
Hyperkalemia or elevated baseline serum potassium precluding safe therapy initiation
Trial design
Treatments tested in this trial
- Epic-Based Clinician Notification
- Usual Care