The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU).
There are two groups of subjects in this study: PICU clinicians/sepsis stakeholders and patients admitted to one of the participating PICUs during the study period. The intervention will at a minimum include:
* Implementation of a clinical guideline indicating when vancomycin should and should not be used * Unit-level feedback on overall vancomycin use within and across centers * Clinician education.
Admitted to one of the participating PICUs during the study period
None
PICU prescribing clinician (including attending physicians, fellows, residents, nurse practitioners, and physician assistants) OR sepsis stakeholder (leader of sepsis quality improvement work, medical director) at one of the participating sites at the time the survey is deployed
Age ≥ 18 years old
Employed by one of the participating sites
Children's Hospital of Philadelphia
Lead sponsor
Children's Healthcare of Atlanta
Collaborator
St. Louis Children's Hospital
Collaborator
Johns Hopkins University
Collaborator
University of Pennsylvania
Collaborator
Centers for Disease Control and Prevention
Collaborator