This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program. They were divided into experimental group and control group according to whether the treatment plan was formulated by a multidisciplinary team. Patients of experimental group is strictly in accordance with standardized multi-disciplinary treatment protocols and meet the following criteria: 1. A multi-disciplinary conference discussion; 2. Detailed preoperative evaluation based on CT, MRI, fMRI and DSA. 3. Treatment modalities meet the following treatment criteria（craniotomy, embolization and stereotactic radiosurgery）. The control group was patients who had not been treated according to a multi-disciplinary treatment protocol.
Patient baseline data, AVM angioarchitectural features, imaging DICOM data, surgical information, and follow-up information were registered. All patients were evaluated for neurofunction at baseline, 3 months, 12 months, and 3 years after treatment. Main observation endpoints: 1. Modified Rankin Scale; 2. Obliteration rate; 3. Subsequent hemorrhage; 4. Complication rate (such as morbidity rate, new-onset neurological dysfunction, and radiation-related complications). Secondary observation endpoint: improvement of clinical symptoms (epilepsy, headache, neurological dysfunction) at 3 months, 12 months, and 3 years after treatment.
The diagnosis of AVM was confirmed with digital subtraction angiography (DSA) and/or magnetic resonance imaging(MRI).
Patients with complete clinical and imaging data.
Patient or patient's legal representative agreed to collection of information for this study and signed informed consent.
Received other treatment (surgery, embolization or SRS)before inclusion;
Expected survival time is less than 6 months;
Spinal AVMs;
Patients missing critical baseline and imaging data.
Beijing Tiantan Hospital
Lead sponsor
Beijing Neurosurgical Institute
Collaborator
Peking University International Hospital
Collaborator
West China Hospital
Collaborator
First Affiliated Hospital of Harbin Medical University
Collaborator
Sichuan Provincial People's Hospital
Collaborator
The First Hospital of Jilin University
Collaborator
Shanxi Provincial People's Hospital
Collaborator
The Second Hospital of Shandong University
Collaborator
The First Affiliated Hospital of Zhengzhou University
Collaborator
First Affiliated Hospital of Xinjiang Medical University
Collaborator
The General Hospital of Central Theater Command
Collaborator
The Affiliated Hospital Of Guizhou Medical University
Collaborator
First Affiliated Hospital of Guangxi Medical University
Collaborator
Tianjin Medical University Second Hospital
Collaborator
The First Affiliated Hospital of Shanxi Medical University
Collaborator
Shengjing Hospital
Collaborator
Second Affiliated Hospital of Guangzhou Medical University
Collaborator
Hainan People's Hospital
Collaborator
The Second Affiliated Hospital of Kunming Medical University
Collaborator
The Affiliated Hospital of Qingdao University
Collaborator
Second Xiangya Hospital of Central South University
Collaborator
Second Affiliated Hospital of Soochow University
Collaborator
General Hospital of Ningxia Medical University
Collaborator
Lanzhou University Second Hospital
Collaborator
The First Affiliated Hospital of Anhui Medical University
Collaborator
First Affiliated Hospital of Zhejiang University
Collaborator
Qilu Hospital of Shandong University
Collaborator
Jining Medical University
Collaborator
First Affiliated Hospital of Chongqing Medical University
Collaborator
First Affiliated Hospital of Fujian Medical University
Collaborator
Shandong Provincial Hospital
Collaborator
The Affiliated Hospital of Xuzhou Medical University
Collaborator
Henan Provincial People's Hospital
Collaborator
Binzhou Medical University
Collaborator
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Collaborator