Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorGeneral University Hospital, Prague
About this trial
The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.
Eligibility criteria
Qualifiers
squamocolumnar junction fully visualized
bioptically verified CIN 2 or CIN 3
age ≥ 18 years
age ≤ 40 years
Disqualifiers
squamocolumnar junction not fully visualized
suspicion on glandular lesion
suspicion on invasive cancer
personal history of CIN 2, 3 or cerv. cancer
Trial design
Treatments tested in this trial
- Colposcopy
Treatment groups
300 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov