Reproductive Hormones During Sustained Administration of Kisspeptin
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorImperial College London
About this trial
We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each month, using either placebo (saline) or kisspeptin in doses of 0.1, 0.3 or 1.0 nmol/kg/hour.
Eligibility criteria
Qualifiers
Aged 18-60 years old
Ability to give informed consent
Secondary hypogonadism (or healthy participant)
Disqualifiers
anaemia
medical problems such as severe heart, kidney or liver disease
blood donation in the last three months or intention to donate blood within 3 months of the end of the study
needle phobia
Trial design
Treatments tested in this trial
- Kisspeptin 0.1
- Saline
- Kisspeptin 0.3
- Kisspeptin 1.0
Treatment groups
76 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov