Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

ConditionsAnxiety Disorders Trauma Generalized Anxiety Disorder Panic Disorder Agoraphobia Illness Anxiety Disorder Social Anxiety Disorder Posttraumatic Stress Disorder Acute Stress Disorder Adjustment Disorder With Anxious Mood

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorUniversity of Texas at Austin

About this trial

Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced respiratory alkalosis and its associated fear-eliciting somatic reactions. Psycho-education about anxiety and its effects (PsyEd) will serve as a credible control comparator.

Eligibility criteria

Qualifiers

Clinically elevated anxiety as indicated by an eight or higher on the Overall Anxiety Severity and Impairment Scale (OASIS).

Generalized Anxiety Disorder

Panic Disorder

Health Anxiety

Disqualifiers

Cardiovascular or respiratory disorders

High blood pressure

Epilepsy

Strokes

Trial design

Treatments tested in this trial

Capnometry-Guided Respiratory Intervention
Psycho-Education

Treatment groups

180 Participants

are divided into 2 treatment groups

Sponsors and collaborators

University of Texas at Austin

Lead sponsor

Freespira, Inc.

Collaborator

Source ClinicalTrials.gov