Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAustralian and New Zealand Intensive Care Research Centre
About this trial
A prospective, individual patient data meta-analysis (IPDMA) of four multicentre, open-label, randomised clinical trials of initial haemodynamic resuscitation in patients with septic shock.
Eligibility criteria
Qualifiers
Suspected or proven infection
Systolic blood pressure (SBP) <100 mm Hg OR mean arterial pressure (MAP) <65 mm Hg
Lactate ≥ 2.0 mmol/L
Requirement for vasopressors to meet perfusion targets
Disqualifiers
None
Trial design
Treatments tested in this trial
- Vasopressors
- Fluids
Treatment groups
7,838 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov