Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDuke University
About this trial
The purpose of this study is to compare brain function after surgical circulatory arrest using either antegrade perfusion or retrograde perfusion.
Eligibility criteria
Qualifiers
> 18 years of age
Participant's that are scheduled for elective proximal aortic reconstructive surgery (ascending aorta + aortic valve or root) with concomitant proximal hemi-arch replacement via median sternotomy
Disqualifiers
< 18 years of age
history of symptomatic cerebrovascular disease, e.g., prior stroke with residual deficit
current alcoholism (> 2 drinks/day)
current psychiatric illness requiring pharmacotherapy
Trial design
Treatments tested in this trial
- Antegrade Perfusion
- Retrograde Perfusion
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov