About this trial
Fluid replacement is considered the cornerstone of hemodynamic management in critically ill patients especially in patients with septic shock. However, only about 50% of critically ill hemodynamically unstable patients are responsive to fluids. Consequently, the resuscitation of critically ill patients requires an accurate assessment of the patients' intravascular volume status and their volume responsiveness. In this study, we will compare the efficacy of carotid artery flow to echo left ventricular end diastolic volume as a predictive value for fluid resuscitation in septic shock patients.
Eligibility criteria
Qualifiers
▪ Age:18-50 years old
Sex: both males &females.
Patients diagnosed with septic shock according to SOFA score more than or equal 1
Low blood pressure (mean arterial pressure <65 mmHg and / or systolic <90 mmHg).
Disqualifiers
▪ Known significant valvular heart disease (sever aortic insufficiency or stenosis)
Known carotid artery stenosis >50% or previous carotid surgery
Clear contraindication to the carotid artery Doppler such as wound or infection or complete or partial occlusion of the carotid artery.
Arrhythmias affect stroke volume assessment (atrial fibrillation, frequent PVCs)
Trial design
Treatments tested in this trial
- carotid artery duplex
- Left ventricular end diastolic area