Pilot study to evaluate the effect of real time continuous glucose monitoring (RT-CGM) on young-adults with insulin-treated diabetes, who are defined as high risk due to suboptimal HbA1c (blood glucose control) or a history of hospital admissions for high blood glucoses.
Hypothesis: RT-CGM provided to young adults with suboptimal blood glucose control, has a beneficial impact on HbA1c and hospital admissions for high blood glucoses. We will use data from this pilot work to inform a larger powered study to address this knowledge gap.
Adolescents and young adults aged 18-25 years
Insulin-treated diabetes >12 months (on multiple daily injections or insulin pump therapy)
HbA1c > 75 mmol/mol (9%) or 1 or more DKA admissions in the last 12 months or 1 or more admissions with uncontrolled blood glucose levels in the last 12 months.
Naïve to RT-CGM - except for short periods for use for diagnosis or monitoring purposes.
Chronic kidney disease eGFR <30ml/min
Pregnant or planning pregnancy
Breastfeeding
Have active malignancy or under investigation for malignancy
Imperial College London
Lead sponsor
DexCom, Inc.
Collaborator