About this trial
The purpose of this study is to explore the safety and efficacy of remote ischemic conditioning in patients with internal carotid artery occlusion receiving hybird surgery.
Eligibility criteria
Qualifiers
Age≥18 years, regardless of sex
Patients with chronic carotid artery occlusion who are going to undergo hybird surgery
Can cooperate with and complete brain magnetic resonance imaging (MRI) examination
Signed and dated informed consent is obtained
Disqualifiers
Hemorrhagic stroke
Severe cardiac dysfunction or arrhythmia
Uncontrolled hypertension (defined as systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg, despite medication taken at enrollment)
Severe hepatic and renal dysfunction (defined as aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≥3 times higher than the upper limit of the normal range, creatinine >265umol/l (3mg/dl))
Trial design
Treatments tested in this trial
- Remote ischemic conditioning
- Sham remote ischemic conditioning
Treatment groups
Locations
Sponsors and collaborators
Yi Yang
Lead sponsor
The First Hospital of Jilin University
Sponsor institution