Safety and Efficacy of Remote Ischemic Conditioning in Patients with Chronic Internal Carotid Artery Occlusion Receiving Hybird Surgery: a Pilot, Randomized Controlled Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorYi Yang

About this trial

The purpose of this study is to explore the safety and efficacy of remote ischemic conditioning in patients with internal carotid artery occlusion receiving hybird surgery.

Eligibility criteria

Qualifiers

Age≥18 years, regardless of sex

Patients with chronic carotid artery occlusion who are going to undergo hybird surgery

Can cooperate with and complete brain magnetic resonance imaging (MRI) examination

Signed and dated informed consent is obtained

Disqualifiers

Hemorrhagic stroke

Severe cardiac dysfunction or arrhythmia

Uncontrolled hypertension (defined as systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg, despite medication taken at enrollment)

Severe hepatic and renal dysfunction (defined as aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≥3 times higher than the upper limit of the normal range, creatinine >265umol/l (3mg/dl))

Trial design

Treatments tested in this trial

  • Remote ischemic conditioning
  • Sham remote ischemic conditioning

Treatment groups

60 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Yi Yang

Lead sponsor

The First Hospital of Jilin University

Sponsor institution