About this trial
This is a national, multicenter, open-label, randomized, controlled, endpoint-blinded clinical trial of patients diagnosed with ATAAD and undergoing "Sun's procedure" coordinated by the First Affiliated Hospital of Xi'an Jiaotong University, China. Per the protocol, "Sun's procedure" combined with "XJ-Procedure" in the anastomosis of the aortic root and Sun's procedure combined with regular suturing methods of the aortic root will be compared.
Eligibility criteria
Qualifiers
Age 18-70 years;
Patients with ATAAD attending the relevant department who have been assessed by a clinician as needing "Sun's procedure".
Disqualifiers
Severe aortic root involvement (root diameter >45 mm, root tear, severe destruction of the aortic root, combined valve disease);
Combined coronary artery disease requiring concomitant coronary revascularization;
Prior aortic or cardiac surgery;
Preoperative severe malperfusion syndromes such as: severe cerebral complications (acute cerebral infarction, cerebral hemorrhage, coma, etc.); malperfusion of abdominal organs or lower extremities >12 h;
Trial design
Treatments tested in this trial
- Vascular Grafts Eversion and Built-in Technique(XJ-Procedure)
Treatment groups
Sponsors and collaborators
First Affiliated Hospital Xi'an Jiaotong University
Lead sponsor
Zhejiang Provincial People's Hospital
Collaborator
Second Affiliated Hospital of Nanchang University
Collaborator
Qinghai People's Hospital
Collaborator