Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorFirst Affiliated Hospital Xi'an Jiaotong University

About this trial

This is a national, multicenter, open-label, randomized, controlled, endpoint-blinded clinical trial of patients diagnosed with ATAAD and undergoing "Sun's procedure" coordinated by the First Affiliated Hospital of Xi'an Jiaotong University, China. Per the protocol, "Sun's procedure" combined with "XJ-Procedure" in the anastomosis of the aortic root and Sun's procedure combined with regular suturing methods of the aortic root will be compared.

Eligibility criteria

Qualifiers

Age 18-70 years;

Patients with ATAAD attending the relevant department who have been assessed by a clinician as needing "Sun's procedure".

Disqualifiers

Severe aortic root involvement (root diameter >45 mm, root tear, severe destruction of the aortic root, combined valve disease);

Combined coronary artery disease requiring concomitant coronary revascularization;

Prior aortic or cardiac surgery;

Preoperative severe malperfusion syndromes such as: severe cerebral complications (acute cerebral infarction, cerebral hemorrhage, coma, etc.); malperfusion of abdominal organs or lower extremities >12 h;

Trial design

Treatments tested in this trial

  • Vascular Grafts Eversion and Built-in Technique(XJ-Procedure)

Treatment groups

680 Participants
are divided into 2 treatment groups

Sponsors and collaborators

First Affiliated Hospital Xi'an Jiaotong University

Lead sponsor

Zhejiang Provincial People's Hospital

Collaborator

Second Affiliated Hospital of Nanchang University

Collaborator

Qinghai People's Hospital

Collaborator