Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorThe First Affiliated Hospital of Guangzhou Medical University

About this trial

Brief Summary

The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are confirmed to have no persistent air leak intraoperatively.

The main questions it aims to answer are:

Does double intraoperative aspiration tubeless strategy reduce the rate of postoperative pleural re-intervention within 30 days compared with single intraoperative aspiration tubeless strategy?

Do different intraoperative pleural space management strategies affect early postoperative recovery quality and pain?

If there is a comparison group:

Researchers will compare conventional chest tube drainage, single intraoperative aspiration tubeless, and double intraoperative aspiration tubeless strategies to determine their effects on postoperative pleural re-intervention and recovery outcomes.

Participants will:

Undergo uniportal VATS wedge resection

Receive a standardized intraoperative air leak test before chest closure

Be randomly assigned intraoperatively to one of three pleural space management strategies

Complete postoperative assessments including chest imaging, pain evaluation, and recovery quality questionnaires

Be followed for 30 days after surgery for safety outcomes

Eligibility criteria

Qualifiers

Age 18 to 80 years

Scheduled to undergo uniportal video-assisted thoracoscopic (VATS) wedge resection

Able to tolerate general anesthesia and single-lung ventilation

Passed a standardized intraoperative water-seal air leak test, confirming absence of persistent air leak before chest closure

Disqualifiers

Planned anatomical lung resection (segmentectomy or lobectomy) or combined complex thoracic procedures

Extensive pleural adhesions, severe emphysema, bullous lung disease, or other conditions associated with high risk of air leak

Positive intraoperative air leak test indicating persistent air leak

Requirement for additional intraoperative procedures that may significantly affect pleural air leak or lung re-expansion

Trial design

Treatments tested in this trial

  • Conventional Chest Tube Drainage
  • Single Intraoperative Aspiration Tubeless
  • Double Intraoperative Aspiration Tubeless

Treatment groups

300 Participants
are divided into 3 treatment groups