Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorGöteborg University

About this trial

Obesity is a growing epidemic throughout the world and is followed by increasing incidence of type 2 diabetes that accounts for 90-95% of all cases of diabetes. Weight loss is a major objective, although difficult to achieve with medical treatments. Many recent studies demonstrated that bariatric surgery has the potency to achieve marked and sustained weight loss, and is also associated with a significant improvement in control of type 2 diabetes. The principal aim of this study is to compare two types of bariatric procedures, the Roux-en-Y gastric bypass (RYGBP) and sleeve gastrectomy (SG). The study hypothesis is that these procedures have equal efficacy with regard to resolution of type 2 diabetes.

Eligibility criteria

Qualifiers

Type 2 diabetes mellitus

BMI between 35 and 50kg/m2.

Males and females

Age between 18 and 60 years.

Disqualifiers

Severe ongoing psychiatric disorder, alcoholism and substance abuse.

Redo operations after previous bariatric procedures.

Type 1 diabetes or other non-type 2 forms of diabetes

End stage renal disease, retinopathy, neuropathy

Trial design

Treatments tested in this trial

  • Roux-en-Y gastric bypass
  • sleeve gastrectomy

Treatment groups

134 Participants
are divided into 2 treatment groups

Sponsors and collaborators