Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBeijing Anzhen Hospital
About this trial
The goal of this multicenter, randomized trial is to compare standby cannulated ECMO versus prophylactic ECMO in patients undergoing high-risk percutaneous coronary intervention (PCI). The main question it aims to answer is :
• If standby cannulated ECMO as compared with prophylactic ECMO will improve the outcomes in patients undergoing high-risk PCI
Eligibility criteria
Qualifiers
Clinicians decide to perform PCI during ECMO support.
Age of ≥18
Patient presents with a compromised ejection fraction of less than 35% or at risk of hemodynamic deterioration, or intervention on the last patent coronary conduit or an unprotected left main artery, or complex 3-vessel disease (SYNTAX score of ≥33)
Informed consent
Disqualifiers
Subject in cardiogenic shock(need inotrope, pressor or mechanical support to maintain SBP >90mmHg)
Presence of moderate to severe aortic insufficiency
Severe peripheral vascular disease
creatinine≥4mg/dL
Trial design
Treatments tested in this trial
- Standby cannulated ECMO
- Prophylactic ECMO
Treatment groups
176 Participants
are divided into 2 treatment groupsSponsors and collaborators
Beijing Anzhen Hospital
Lead sponsor
Wuhan Asia Heart Hospital
Collaborator
First Affiliated Hospital of Harbin Medical University
Collaborator
People's Hospital of Xinjiang Uygur Autonomous Region
Collaborator
People's Hospital of Guangxi Zhuang Autonomous Region
Collaborator
The First Affiliated Hospital of Lanzhou Medical University
Collaborator
Chinese Academy of Medical Sciences, Fuwai Hospital
Collaborator
The Second Affiliated Hospital of Harbin Medical University
Collaborator
Source ClinicalTrials.gov