Study on MRD Prediction of Efficacy of Toripalimab in the Treatment of High-risk Recurrent Renal Carcinoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorTianjin Medical University Second Hospital

About this trial

This is a prospective cohort study aimed at clarifying the predictive value of MRD for postoperative DFS and OS in high-risk recurrent renal cell carcinoma patients who have undergone radical nephrectomy and received adjuvant treatment with Toripalimab. Further differentiating patients who need adjuvant immunotherapy.

Eligibility criteria

Qualifiers

There must be a histological diagnosis of renal cell carcinoma, with or without sarcomatoid features of clear cell components.

On the day of signing the informed consent form, both males and females must be at least 18 years old.

The participants provide written informed consent for the trial before enrollment.

Have high risk or M1 NED renal cell carcinoma as defined by the following pathological tumor-node-metastasis and Fuhrman grading status.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Toripalimab

Treatment groups

110 Participants
are divided into 1 treatment group