Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorThe Affiliated Hospital Of Guizhou Medical University

About this trial

To compare the neurological recovery and complication rate of autogenous cranioplasty(CP) within 6 weeks after decompressive craniectomy (DC) with that of autogenous cranioplasty within 3\~6 months after DC.

Eligibility criteria

Qualifiers

Decompressive craniectomy due to craniocerebral trauma, cerebral ischemia and cerebral hemorrhage.

Age 18 - 80 years.

The first time for cranial repair.

unilateral skull defect.

Disqualifiers

Poor healing of skin flap (active infection, non-healing, necrosis, sinus, thin or poor blood supply, etc.).

Fracture of bone flap ≥2 pieces, partial open fracture

Intracranial infection before operation.

Severe bone metabolic diseases.

Trial design

Treatments tested in this trial

  • operation opportunity-within 6 weeks after the DC operation.
  • operation opportunity-within 90 to 180 days after the DC operation.

Treatment groups

582 Participants
are divided into 2 treatment groups