Cranial Defect

3

Review clinical trials related to Cranial Defect. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Associations of Cranial Outcomes and Parental Expectations and Satisfaction

This study aims to investigate the association between objective cranial morphological changes and parental expectations and satisfaction in infants undergoing treatment with a cranial remolding orthosis (CRO). Infants diagnosed with positional cranial deformities and prescribed CRO treatment will be included. Cranial morphological outcomes will be assessed using standardized cranial measurements obtained before and after the treatment period. Parental treatment expectations will be evaluated prior to the initiation of CRO therapy using the Treatment Expectation Questionnaire (TR.TEX-Q), while parental satisfaction with the device and treatment process will be assessed at the end of treatment using the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST). The primary objective of the study is to examine the relationships between changes in cranial morphology and parental expectations and satisfaction scores. Secondary objectives include exploring the association between baseline expectations and post-treatment satisfaction. The findings are expected to provide insight into how objective treatment outcomes align with family-reported perceptions in cranial remolding orthosis therapy.

Participants needed: 20
Trial details
Age: 3-18Biological sex: AllType: ObservationalSponsor: Gulhane School of MedicineUpdated: Jan 26, 2026Locations: 1Duration: 1 Month
Eligibility criteria

Infants diagnosed with positional cranial deformities (e.g., plagiocephaly, brac... [+5]

Infants with neurological disorders, genetic syndromes, or congenital conditions... [+5]

Status: Not yet recruiting

Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery

To compare the neurological recovery and complication rate of autogenous cranioplasty(CP) within 6 weeks after decompressive craniectomy (DC) with that of autogenous cranioplasty within 3\~6 months after DC.

Participants needed: 582
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: The Affiliated Hospital Of Guizhou Medical UniversityUpdated: Sep 19, 2025Locations: 7
Eligibility criteria

Decompressive craniectomy due to craniocerebral trauma, cerebral ischemia and ce... [+5]

Poor healing of skin flap (active infection, non-healing, necrosis, sinus, thin... [+13]

Status: Recruiting

A Prospective Observational Study of Transcranial Doppler Ultrasound in the Assessment of Cerebral Blood Flow After Polyetheretherketone Cranioplasty

Polyetheretherketone has become one of the most important material choices for cranioplasty surgery. It has been shown that conventional ultrasound can be performed through the polyetheretherketone material for the examination of brain tissue and ventricular morphology. Transcranial doppler ultrasound can obtain good images of cerebral hemodynamic parameters in patients through polyetheretherketone-covered temporal window. This trial is a clinical prospective observational study in which cases treated with polyetheretherketone cranioplasty, and transcranial doppler ultrasonography is performed preoperatively and 10 days postoperatively, and data were collected mainly including bilateral hemodynamic parameters of middle cerebral artery(MCA), terminal internal carotid artery(TICA), (anterior communicating artery)ACA, and posterior cerebral artery(PCA) (Vs, Vd, Vm, PI index, RI index) from temporal window.

Participants needed: 10
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: RenJi HospitalUpdated: Nov 15, 2024Locations: 2
Eligibility criteria

Age of 18 years or older; [+3]