Surgical Glove Compression to Prevent Paclitaxel Neuropathy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-80
SponsorNecmettin Erbakan University
About this trial
This study aims to evaluate the effect of surgical glove compression as a prophylactic method to prevent paclitaxel-induced peripheral neuropathy. Participants will be randomly assigned to two groups: one receiving standard care, and the other receiving prophylactic surgical glove compression. The study will compare the development, severity of neuropathy in the hands and fingers, and its impact on quality of life.
Eligibility criteria
Qualifiers
Patients aged between 18 and 80 years
Diagnosed with Stage II-III breast cancer
No distant metastasis
Planned to receive adjuvant or neoadjuvant paclitaxel for at least 12 weeks
Disqualifiers
Recurrent breast cancer
Prior treatment associated with neuropathy (e.g., taxanes, platinum-based chemotherapy, anti-tubulin or proteasome inhibitors)
Trial design
Treatments tested in this trial
- Surgical glove compression during paclitaxel infusion
Treatment groups
84 Participants
are divided into 3 treatment groupsSponsors and collaborators
Necmettin Erbakan University
Lead sponsor
Konya City Hospital
Sponsor institution
Source ClinicalTrials.gov