Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorRush University Medical Center
About this trial
The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (ACL) rupture of the knee.
Eligibility criteria
Qualifiers
Age 18 - 50
English-speaking
Clinical evidence of ACL rupture with swelling
Participant must be undergoing ACL reconstruction surgery
Disqualifiers
Age <18 or >50
Presentation >3 weeks after initial injury
Previous traumatic ipsilateral (same side) knee injury consistent with chronic ACL tear or prior ACL surgery
> Kellgren-Lawrence grade 2 changes on preoperative x-ray
Trial design
Treatments tested in this trial
- Synovial Fluid withdrawal at the preoperative clinic visit
- Platelet-Rich Plasma (PRP) preparation and injection
- Synovial fluid withdrawal at the time of surgery
- 3mL synovial fluid withdrawn at the preoperative visit
Treatment groups
99 Participants
are divided into 3 treatment groupsSponsors and collaborators
Rush University Medical Center
Lead sponsor
Arthroscopy Association of North America
Collaborator
Source ClinicalTrials.gov